Replication Data for: Genomic analysis of respiratory syncytial virus infections in households and utility in inferring who infects the infant

Agoti, CN; Plan, MVT; Munywoki, PK; Githinji, G; Medley, GFORCID logo; Cane, PA; Kellam, P; Cotten, MORCID logo and Nokes, DJ (2019). Replication Data for: Genomic analysis of respiratory syncytial virus infections in households and utility in inferring who infects the infant. [Dataset]. Harvard Dataverse. https://doi.org/10.7910/DVN/DUCQWE
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This dataset contains whole genomic sequences (WGS) obtained from participants enrolled in a household study undertaken within Kilifi County, located in coastal Kenya. In the study, 47 households (HH) scattered across an area of approximately 21 km2 were followed up over a 6-month period beginning December 2009 and ending June 2010 coinciding with the RSV peak activity months in the area. Twice weekly throughout the study period, a nasopharyngeal-flocked swab (NPS) was obtained from each household member regardless of symptom status. The NPS samples were screened for a range of respiratory viral targets using a multiplex real-time RT-PCR method which subtyped RSV positives into RSVA and RSVB. The whole genome sequencing (WGS) present in this dataset targeted 20 select households that documented RSV infection of ≥2 members.

Keywords

Whole genomic sequences

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