Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study

Brauer, R; Bhaskaran, K; Chaturvedi, N; Dexter, DT; Smeeth, L and Douglas, I (2015). Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study. [Dataset]. Figshare, London, United Kingdom. 10.1371/journal.pmed.1001854.
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Study instruments supporting a retrospective cohort study that explored potential links between prescription of anti-diabetic glitazone (GTZ) drugs and incidence of Parkinson’s disease. Outputs include: information on patient demographics and characteristics; codes used to identify GTZ exposure; codes used to identify Parkinson’s disease; variable code listings; a checklist of items to be included in cohort study reports; an ISAC application form; and a CPRD research protocol.

Keywords

Retrospective Cohort Study; PPAR gamma pathways; Prescription; Parkinson's disease diagnosis; Incidence rate ratio; GTZ; Antidiabetic; Diabetes treatment stage; Glitazone

Item Type Dataset
Resource Type
Resource Type
Resource Description
Dataset
UNSPECIFIED
Capture method Aggregation
Collection Period
From
To
October 2013
October 2013
Date 21 July 2015
Language(s) of written materials English
Creator(s) Brauer, R; Bhaskaran, K; Chaturvedi, N; Dexter, DT; Smeeth, L and Douglas, I
LSHTM Faculty/Department Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Participating Institutions London School of Hygiene & Tropical Medicine; University College London; Imperial College
Funders
Project
Funder
Grant Number
Funder URI
UNSPECIFIED
Michael J. Fox Foundation for Parkinson’s Research
UNSPECIFIED
UNSPECIFIED
UNSPECIFIED
Medical Research Council
UNSPECIFIED
UNSPECIFIED
UNSPECIFIED
NHS National Institute for Health Research
UNSPECIFIED
UNSPECIFIED
UNSPECIFIED
Wellcome Trust
UNSPECIFIED
UNSPECIFIED
Date Deposited 22 Jan 2016 10:51
Last Modified 28 Sep 2018 21:18
Publisher Figshare

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Data / Code

S1_Table-CSV.csv
subject
Data
Available under Creative Commons: Attribution 3.0
info
Patient demographics and characteristics: Individuals diagnosed with PD versus individuals not diagnosed with PD
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2kB
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S1_Table-MSWord.doc
subject
Data
Available under Creative Commons: Attribution 3.0
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Patient demographics and characteristics: Individuals diagnosed with PD versus individuals not diagnosed with PD
description
application/msword
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37kB
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Documentation

S1_Text.pdf
subject
Documentation
Available under Creative Commons: Attribution 3.0
info
Codes used to identify GTZ exposure
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194kB
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S2_Text.pdf
subject
Documentation
Available under Creative Commons: Attribution 3.0
info
Codes used to identify PD: PD with no identified cause and PD with identified causes
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S3_Text.docx
subject
Documentation
Available under Creative Commons: Attribution 3.0
info
Codes used for variables listed in Table 1
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application/vnd.openxmlformats-officedocument.wordprocessingml.document
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31kB
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Study Instrument

S1_Protocol.pdf
subject
Study Instrument
Available under Creative Commons: Attribution 3.0
info
ISAC application form - Protocol for research using the CPRD
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application/pdf
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897kB
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S1_STROBE_Checklist.pdf
subject
Study Instrument
Available under Creative Commons: Attribution 3.0
info
Checklist of items that should be included in reports of cohort studies
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282kB
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