A seroepidemiological study of serogroup A meningococcal infection in the African meningitis belt

The dataset contains results of a cross-sectional survey of meningococcal carriage and immunity performed in several countries of the African meningitis belt in 2010. A standardised enzyme-linked immunosorbent assay (ELISA) for measuring meningococcal serogroup A IgG antibodies was used to measure antibody concentrations in 3930 individuals. Anonymised information on the age, sex, residence, carriage status and other risk factors is included.

Alternative Title

Une étude séro-épidémiologique de l' infection à méningocoque du sérogroupe A dans la ceinture africaine de la méningite

Additional Information

The survey was performed prior to the introduction of data sharing requirements. Therefore, it was not addressed in the original participant consent form. To fulfill PLOS expectations in this area, the study team sought advice from the LSHTM Ethics Committee in December 2015. Specifically, they requested permission to upload an anonymised dataset to the repository and make it available as request access through a 'gatekeeper'. The LSHTM Ethics Committee approved the request in January 2016, stating that it was in keeping with the intent of the original consent process.

Keywords

Meningitis; Neisseria meningitidis; ELISA; Antibody; Seroprevalence