Evidence for Community Transmission of Community-Associated but Not Health-Care-Associated Methicillin-Resistant Staphylococcus Aureus Strains Linked to Social and Material Deprivation: Spatial Analysis of Cross-sectional Data
Identifying and tackling the social determinants of infectious diseases has become a public health priority following the recognition that individuals with lower socioeconomic status are disproportionately affected by infectious diseases. In many parts of the world, epidemiologically and genotypically defined community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) strains have emerged to become frequent causes of hospital infection. The aim of this study was to use spatial models with adjustment for area-level hospital attendance to determine the transmission niche of genotypically defined CA- and health-care-associated (HA)-MRSA strains across a diverse region of South East London and to explore a potential link between MRSA carriage and markers of social and material deprivation.
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Keywords
Methicillin-resistant Staphylococcus aureus; Socioeconomic aspects of health; Ethnic epidemiology; Nosocomial infections; Census; Housing; Theoretical ecology; Spatial epidemiologyData / Code
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subject - Data
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- Available under Creative Commons: Attribution 3.0
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info - S1 Table. Summary statistics for area-level variables in 513 LSOAs within catchment areas of the hospital cohort
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subject - Data
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info - S1 Table. Summary statistics for area-level variables in 513 LSOAs within catchment areas of the hospital cohort.
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- 89kB
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subject - Data
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info - S1 Text. Individual patient-level metadata
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subject - Data
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info - S1 Text. Individual patient-level metadata
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subject - Data
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info - S2 Text. LSOA-level aggregated metadata and dictionary
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subject - Data
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info - LSOA-level aggregated metadata in CSV format
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subject - Data
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info - S2 Table. Population structure of 513 LSOAs within catchment areas of the hospital cohort
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subject - Data
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info - S2 Table. Population structure of 513 LSOAs within catchment areas of the hospital cohort
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Documentation
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subject - Documentation
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- Available under Creative Commons: Attribution 3.0
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info - S1 Methods. Description of modelling approach
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subject - Documentation
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info - Data dictionary for LSOA aggregated dataset
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