Comparative genomic analyses of Trypanosoma cruzi experimental hybrids

Matos, GM; Lewis, MDORCID logo; Talavera-López, C; Yeo, MORCID logo; Grisard, EC; Messenger, LA; Miles, MAORCID logo and Andersson, B (2021). Comparative genomic analyses of Trypanosoma cruzi experimental hybrids. [Dataset]. NCBI BioProject. https://www.ncbi.nlm.nih.gov/bioproject/PRJNA748998
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To investigate the effects of clonal reproduction and genetic exchange on the T. cruzi genome we selected two closely related TcI strains (P1, P2) and three hybrid clones that were generated from a P1 x P2 cross (1C2, 1D12, 2C1) (Gaunt et al. 2003). We have used whole genome sequencing to characterize both the parental and hybrid strains, as well as three clone isolates of each parental and hybrid strain after 800 generations of growth in vitro.

Alternative Title

PRJNA748998

Additional Information

The dataset author list is described in the 'Data Availability' section of 10.7554/eLife.75237.

Keywords

Genetics and Genomics; Microbiology and Infectious Disease; Trypanosoma cruzi; Genetic exchange; Comparative genomics; Microevolution

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